Before your procedure, you will get medicine through a vein your arm (called an IV). The medicine will help you relax and feel sleepy. There are different types of sedation:
Most GI procedures use moderate sedation or deep sedation. General anesthesia may be needed for longer or more complicated procedures, or if you have medical problems that make sedation risky. Your sedation may be managed by your GI doctor and a trained sedation nurse or by a specialist called an anesthesia provider. Deep sedation and general anesthesia are usually given by an anesthesia provider. Sometimes, sedation by an anesthesia provider may cost extra on your insurance.</p
Without sedation: Some people choose to have their procedure without sedation. If you choose this, you will be awake during the procedure. You might feel cramping or discomfort from gas used during the exam. If you prefer this, talk to your healthcare team when you arrive.
Important preparation:
Why is this important? If there is food or liquid in your stomach during sedation, it could cause a serious infection in your lungs called “aspiration.”
Sedation is safe for most people. Problems are very rare - they happen less than 1% of the time. The most common problem is a drop in breathing or heart rate while you are sleepy. You will receive oxygen through a small tube in your nose to keep your oxygen levels normal.
Print the checklist below and share any questions or concerns with your healthcare team before your procedure.
Tell your doctor about any medications you take, including:
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Certain medical conditions are important for the doctor to know about. They include:
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Tell your doctor if you have any allergies, especially to medications. Write down the names of any medicines you are allergic to and share this list with your healthcare team.
Ask questions. If you have any worries or things you are unsure about, ask your healthcare team. Write down your questions.
Even if you feel normal after the procedure, the medicine can stay in your body for several hours. This might slow down your thinking and reaction time. You will need someone to drive you home. Do not go to work or make important decisions until the day after your procedure.
John J. Vargo, II, MD, MPH, FACG, Cleveland Clinic, Cleveland, OH – Published July 2005. Updated November 2008.
Patrick K. McCabe, MD, MEd, Sutter Health, San Francisco, CA – Update February 2020.
J. Royce Groce MD, MS, The Ohio State University, Columbus OH – Update August 2021.
Ann Flynn, MD, FACG, University of Utah Health, Salt Lake City, UT – Update April 2025.